MIF-Induced Mesenchymal Marker in Pancreatic Cancer

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Title: MIF-Induced Mesenchymal Marker in Pancreatic Cancer
Description: Macrophage migration inhibitory factor (MIF) enhances disease aggressiveness and the metastatic potential of pancreatic cancer cells by inducing epithelial-to-mesenchymal transition (EMT). This image, obtained with confocal microscopy, shows enhanced vimentin expression (pink), a mesenchymal marker, in pancreatic cancer cells stably overexpressing MIF.

This image was originally submitted as part of the 2015 NCI Cancer Close Up project.

This image is part of the NCI Cancer Close Up 2015 collection.

See also https://visualsonline.cancer.gov/closeup.
Topics/Categories: Cancer Types -- Pancreatic Cancer
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo
Source: NCI Center for Cancer Research
Creator: Naotake Funamizu, S. Perwez Hussain
Date Created: 2012
Date Added: April 9, 2015
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.