MIF-Induced Mesenchymal Marker in Pancreatic Cancer

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Title: MIF-Induced Mesenchymal Marker in Pancreatic Cancer
Description: Macrophage migration inhibitory factor (MIF) enhances disease aggressiveness and the metastatic potential of pancreatic cancer cells by inducing epithelial-to-mesenchymal transition (EMT). This image, obtained with confocal microscopy, shows enhanced vimentin expression (pink), a mesenchymal marker, in pancreatic cancer cells stably overexpressing MIF.

This image was originally submitted as part of the 2015 NCI Cancer Close Up project.
Topics/Categories: Cancer Types -- Pancreatic Cancer
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo (JPEG format)
Source: NCI Center for Cancer Research
Creator: Naotake Funamizu, S. Perwez Hussain
Date Created: 2012
Date Added: April 9, 2015
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.