Localized RNAs in a Mouse Cell 2

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Title: Localized RNAs in a Mouse Cell 2
Description: RNAs differentially localized in a mouse cell. One RNA population (red) is localized at cell protrusions while another (yellow) is distributed throughout the cytoplasm. Blue cell stain marks the outlines of each cell. Targeting of mRNA molecules to specific subcellular regions can spatially regulate gene expression within individual cells. The tumor suppressor protein APC, whose mutation initiates progression of colorectal cancers, is important for localizing RNAs at the tips of cellular protrusions. Compromising this function in cancer cells could contribute to tumor progression.

This image was originally submitted as part of the 2015 NCI Cancer Close Up project.

This image is part of the NCI Cancer Close Up 2015 collection.

See also https://visualsonline.cancer.gov/closeup.
Topics/Categories: Cells or Tissue -- Normal Cells or Tissue
Type: Color, Photo
Source: NCI Center for Cancer Research
Creator: Tianhong Wang, Voula Mili
Date Created: 2014
Date Added: April 9, 2015
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.