Localized RNAs in a Mouse Cell 2
|Title:||Localized RNAs in a Mouse Cell 2|
RNAs differentially localized in a mouse cell. One RNA population (red) is localized at cell protrusions while another (yellow) is distributed throughout the cytoplasm. Blue cell stain marks the outlines of each cell. Targeting of mRNA molecules to specific subcellular regions can spatially regulate gene expression within individual cells. The tumor suppressor protein APC, whose mutation initiates progression of colorectal cancers, is important for localizing RNAs at the tips of cellular protrusions. Compromising this function in cancer cells could contribute to tumor progression.
This image was originally submitted as part of the 2015 NCI Cancer Close Up project.
This image is part of the NCI Cancer Close Up 2015 collection.
See also https://visualsonline.cancer.gov/closeup.
|Topics/Categories:||Cells or Tissue -- Normal Cells or Tissue|
|Source:||NCI Center for Cancer Research|
|Creator:||Tianhong Wang, Voula Mili|
|Date Added:||April 9, 2015|