Irregular Cell Division in BRCA1-Depleted Cells

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Title: Irregular Cell Division in BRCA1-Depleted Cells
Description: This image shows centrosome amplification as a consequence of loss of the tumor suppressor gene BRCA1, which is responsible for most cases of familial breast cancer. Left panel, normal cell division with two centrosomes; right panel, BRCA1-depleted cell showing an imminent irregular cell division.

This image was originally submitted as part of the 2015 NCI Cancer Close Up project.
Topics/Categories: Cancer Types -- Breast Cancer
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo (JPEG format)
Source: NCI Center for Cancer Research
Creator: Thomas Ried
Date Created: 2014
Date Added: April 9, 2015
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.