Irregular Cell Division in BRCA1-Depleted Cells

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Title: Irregular Cell Division in BRCA1-Depleted Cells
Description: This image shows centrosome amplification as a consequence of loss of the tumor suppressor gene BRCA1, which is responsible for most cases of familial breast cancer. Left panel, normal cell division with two centrosomes; right panel, BRCA1-depleted cell showing an imminent irregular cell division.

This image was originally submitted as part of the 2015 NCI Cancer Close Up project.

This image is part of the NCI Cancer Close Up 2015 collection.

See also
Topics/Categories: Cancer Types -- Breast Cancer
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo (JPEG format)
Source: NCI Center for Cancer Research
Creator: Thomas Ried
Date Created: 2014
Date Added: April 9, 2015
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.