Skin Cancer, Clark Levels

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Title: Skin Cancer, Clark Levels
Description: Clark levels of skin cancer; drawing shows skin with five thin lesions of different depths. In the first lesion (Clark Level I), the cancer is in the epidermis only. In the second lesion (Clark Level II), the cancer has begun to spread into the papillary dermis (upper layer of the dermis). In the third lesion (Clark Level III), the cancer has spread through the papillary dermis into the papillary-reticular dermal interface but not into the reticular dermis (lower layer of the dermis). In the fourth lesion (Clark Level IV), the cancer has spread into the reticular dermis. In the fifth lesion (Clark Level V), the cancer has spread into the subcutaneous tissue.

Clark levels of skin cancer. In Clark Level I, the cancer is in the epidermis only. In Clark Level II, the cancer has begun to spread into the papillary dermis (upper layer of the dermis). In Clark Level III, the cancer has spread through the papillary dermis into the papillary-reticular dermal interface but not into the reticular dermis (lower layer of the dermis). In Clark Level IV, the cancer has spread into the reticular dermis. In Clark Level V, the cancer has spread into the subcutaneous tissue.
Topics/Categories: Anatomy -- Skin
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Medical Illustration
Source: National Cancer Institute
Creator: Terese WInslow (Illustrator)
AV Number: CDR630443
Date Created: April 16, 2009
Date Added: March 8, 2010
Reuse Restrictions: Yes - This image is copyright protected. Any use of this image is subject to prevailing copyright laws. U.S. Government has reuse rights. Please contact the rights holder of this image for permission requests.

Rights holder: Terese Winslow
Email: terese@teresewinslow.com