Philadelphia Chromosome
| Title: | Philadelphia Chromosome |
|---|---|
| Description: | Philadelphia chromosome; three-panel drawing shows a piece of chromosome 9 and a piece of chromosome 22 breaking off and trading places, creating a changed chromosome 22 called the Philadelphia chromosome. In the left panel, the drawing shows a normal chromosome 9 with the ABL1 gene and a normal chromosome 22 with the BCR gene. In the center panel, the drawing shows part of the ABL1 gene breaking off from chromosome 9 and a piece of chromosome 22 breaking off, below the BCR gene. In the right panel, the drawing shows chromosome 9 with the piece from chromosome 22 attached. It also shows a shortened version of chromosome 22 with the piece from chromosome 9 containing part of the ABL1 gene attached. The ABL1 gene joins to the BCR gene on chromosome 22 to form the BCR::ABL1 fusion gene. The changed chromosome 22 with the BCR::ABL1 fusion gene on it is called the Philadelphia chromosome. |
| Topics/Categories: | Science and Technology -- Genetics |
| Type: | Color, Medical Illustration (JPEG format) |
| Source: | National Cancer Institute |
| Creator: | Terese Winslow (Illustrator) |
| AV Number: | CDR533336 |
| Date Created: | November 12, 2024 |
| Date Added: | August 27, 2008 |
| Reuse Restrictions: |
Yes - This image is copyright protected. Any use of this image is subject to prevailing copyright laws. U.S. Government has reuse rights. Please contact the rights holder of this image for permission requests.
Rights holder: Terese Winslow Email: terese@teresewinslow.com |