Philadelphia Chromosome

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Title: Philadelphia Chromosome
Description: Philadelphia chromosome; three-panel drawing shows a piece of chromosome 9 and a piece of chromosome 22 breaking off and trading places, creating a changed chromosome 22 called the Philadelphia chromosome. In the left panel, the drawing shows a normal chromosome 9 with the abl gene and a normal chromosome 22 with the bcr gene. In the center panel, the drawing shows chromosome 9 breaking apart in the abl gene and chromosome 22 breaking apart below the bcr gene. In the right panel, the drawing shows chromosome 9 with the piece from chromosome 22 attached and chromosome 22 with the piece from chromosome 9 containing part of the abl gene attached. The changed chromosome 22 with bcr-abl gene is called the Philadelphia chromosome.

Philadelphia chromosome. A piece of chromosome 9 and a piece of chromosome 22 break off and trade places. The bcr-abl gene is formed on chromosome 22 where the piece of chromosome 9 attaches. The changed chromosome 22 is called the Philadelphia chromosome.
Topics/Categories: Science and Technology -- Genetics
Type: Color, Medical Illustration
Source: National Cancer Institute
Creator: Terese Winslow (Illustrator)
AV Number: CDR533336
Date Created: April 8, 2008
Date Added: August 27, 2008
Reuse Restrictions: Yes - This image is copyright protected. Any use of this image is subject to prevailing copyright laws. U.S. Government has reuse rights. Please contact the rights holder of this image for permission requests.

Rights holder: Terese Winslow
Email: terese@teresewinslow.com