Ultrasmall Targeted Nanoparticles with Engineered Antibody Fragments for Imaging Detection of HER2-Overexpressing Breast Cancer
| Title: | Ultrasmall Targeted Nanoparticles with Engineered Antibody Fragments for Imaging Detection of HER2-Overexpressing Breast Cancer |
|---|---|
| Description: |
PET image of human epidermal growth factor receptor 2 (HER2)–targeting zirconium 89–deferoxamine–single-chain variable fragment–polyethylene glycol–cyanine 5–C’ dots) accumulated in breast cancer xenograft tumors with associated receptors. Source: Chen F, Ma K, Madajewski B, Zhuang L, Zhang L, Rickert K, Marelli M, Yoo B, Turker MZ, Overholtzer M, Quinn TP, Gonen M, Zanzonico P, Tuesca A, Bowen MA, Norton L, Subramony JA, Wiesner U, Bradbury MS. Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer. Nat Commun. 2018 Oct 8;9(1):4141. doi: 10.1038/s41467-018-06271-5. PMID: 30297810; PMCID: PMC6175906. See also www.ncbi.nlm.nih.gov/pmc/articles/PMC6175906/. |
| Topics/Categories: | Science and Technology -- Nanotechnology |
| Type: | Color, Photo (JPEG format) |
| Source: | National Cancer Institute (NCI) |
| Date Created: | Unknown |
| Date Added: | November 15, 2023 |
| Reuse Restrictions: | None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above. |