Nanoparticles Correlating with Trans-Endothelial Pathways of Transport

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Title: Nanoparticles Correlating with Trans-Endothelial Pathways of Transport
Description: Intravital imaging shows colocalization of the nanoparticles with endothelial cells to form hotspots along the vessel lining (red, stained with GSL1-Cy3). Arrows indicate hotspots. These vessels belong to the mouse mammary tumor virus-polyoma middle tumor-antigen (MMTV-PyMT) (c) and 4T1 (d) breast cancer models.

Source: Sindhwani S, Syed AM, Ngai J, Kingston BR, Maiorino L, Rothschild J, MacMillan P, Zhang Y, Rajesh NU, Hoang T, Wu JLY, Wilhelm S, Zilman A, Gadde S, Sulaiman A, Ouyang B, Lin Z, Wang L, Egeblad M, Chan WCW. The entry of nanoparticles into solid tumours. Nat Mater. 2020 May;19(5):566-575. doi: 10.1038/s41563-019-0566-2. Epub 2020 Jan 13. PMID: 31932672.

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Topics/Categories: Science and Technology -- Nanotechnology
Type: Color, Photo (JPEG format)
Source: National Cancer Institute (NCI)
Date Created: Unknown
Date Added: November 15, 2023
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.