Nanomaterials-Induced Endothelial Leakiness (NanoEL) Might Accelerate Metastasis
| Title: | Nanomaterials-Induced Endothelial Leakiness (NanoEL) Might Accelerate Metastasis |
|---|---|
| Description: |
Confocal microscope image of pericellular actin fibers in titanium dioxide nanoparticle-treated cells. Titanium dioxide nanoparticles were found to promote in vivo breast cancer cell intravasation and extravasation subsequently accelerating metastasis by inducing endothelial leakiness. This potential for nanomaterials-induced endothelial leakiness needs to be taken into consideration when designing future nanomedicines, especially nanomedicine to treat cancer. Source: Peng F, Setyawati MI, Tee JK, Ding X, Wang J, Nga ME, Ho HK, Leong DT. Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness. Nat Nanotechnol. 2019 Mar;14(3):279-286. doi: 10.1038/s41565-018-0356-z. Epub 2019 Jan 28. PMID: 30692675. See also pubmed.ncbi.nlm.nih.gov/30692675/. |
| Topics/Categories: | Science and Technology -- Nanotechnology |
| Type: | Color, Photo (PNG format) |
| Source: | National Cancer Institute (NCI) |
| Date Created: | Unknown |
| Date Added: | November 15, 2023 |
| Reuse Restrictions: | None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above. |