Nanostructure-Embedded Microchip That Efficiently Enriches Both Single and Clustered Circulating Trophoblasts (Ctbs) from Maternal Blood for Detecting Placenta Accreta Spectrum (PAS)

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Title: Nanostructure-Embedded Microchip That Efficiently Enriches Both Single and Clustered Circulating Trophoblasts (Ctbs) from Maternal Blood for Detecting Placenta Accreta Spectrum (PAS)
Description: SEM images of single (N = 1) and clustered (N= 2, 3, 4, and >5) JEG-3 placental cells captured on the surface of NanoVelcro Chips. Cells are colored in green. NanoVelcro Chips allow to capture rare cells from maternal blood to diagnose placenta accreta spectrum (PAS), a high-risk obstetrical condition associated with significant morbidity and mortality.

Source: Afshar Y, Dong J, Zhao P, Li L, Wang S, Zhang RY, Zhang C, Yin O, Han CS, Einerson BD, Gonzalez TL, Zhang H, Zhou A, Yang Z, Chou SJ, Sun N, Cheng J, Zhu H, Wang J, Zhang TX, Lee YT, Wang JJ, Teng PC, Yang P, Qi D, Zhao M, Sim MS, Zhe R, Goldstein JD, Williams J 3rd, Wang X, Zhang Q, Platt LD, Zou C, Pisarska MD, Tseng HR, Zhu Y. Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders. Nat Commun. 2021 Aug 3;12(1):4408. doi: 10.1038/s41467-021-24627-2. PMID: 34344888; PMCID: PMC8333096.

See also www.ncbi.nlm.nih.gov/pmc/articles/PMC8333096/.
Topics/Categories: Science and Technology -- Nanotechnology
Type: Color, Photo (JPEG format)
Source: National Cancer Institute (NCI)
Date Created: Unknown
Date Added: November 14, 2023
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.