CAR T-Cell Therapy

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Title: CAR T-Cell Therapy
Description: CAR T-cell therapy; drawing of blood being removed from a vein in a patient’s arm to get T cells. Also shown is a special receptor called a chimeric antigen receptor (CAR) being made in the laboratory; the gene for CAR is inserted into the T cells and then millions of CAR T cells are grown. Drawing also shows the CAR T cells being given to the patient by infusion and binding to antigens on the cancer cells and killing them.

CAR T-cell therapy. A type of treatment in which a patient’s T cells (a type of immune cell) are changed in the laboratory so they will bind to cancer cells and kill them. Blood from a vein in the patient’s arm flows through a tube to an apheresis machine (not shown), which removes the white blood cells, including the T cells, and sends the rest of the blood back to the patient. Then, the gene for a special receptor called a chimeric antigen receptor (CAR) is inserted into the T cells in the laboratory. Millions of the CAR T cells are grown in the laboratory and then given to the patient by infusion. The CAR T cells are able to bind to an antigen on the cancer cells and kill them.
Topics/Categories: Cells or Tissue -- Abnormal Cells or Tissue
Cells or Tissue -- Normal Cells or Tissue
Treatment -- Immunotherapy
Type: Color, Medical Illustration
Source: National Cancer Institute
Creator: Terese Winslow (Illustrator)
AV Number: CDR774647
Date Created: October 23, 2017
Date Added: November 8, 2017
Reuse Restrictions: Yes - This image is copyright protected. Any use of this image is subject to prevailing copyright laws. U.S. Government has reuse rights. Please contact the rights holder of this image for permission requests.

Rights holder: Terese Winslow
Email: terese@teresewinslow.com