Cell Death Wave Using C Dots

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Title: Cell Death Wave Using C Dots
Description: Carbon quantum dots (C dots) are nanoparticles less than 10 nanometers in size. Biomedical researchers are exploring ways to use C dots as drug carriers, fluorescent tags, and more. This image shows cells from a mouse model of melanoma (B16) after treatment with high-dose, melanoma-targeted C dots carrying a therapeutic agent: peptides targeting the melanocortin-1 receptor. After treatment, cancer cells (upper left panel) die by an iron-driven mechanism called ferroptosis (upper right panel, green). This results in death spreading through the cells in a wave-like manner. The lower panel shows the cell death wave, with individual nuclei pseudocolored to represent the relative timing of cell death.
Topics/Categories: Cancer Types -- Melanoma
Science and Technology -- Nanotechnology
Type: Color, Photo (JPEG format)
Source: National Cancer Institute \ MSK-Cornell Center for Translation of Cancer Nanomedicine
Creator: MSK-Cornell Center for Translation of Cancer Nanomedicine
Date Created: January 2017
Date Added: March 20, 2017
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.