Multimodal Imaging with Nanoparticles

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Title: Multimodal Imaging with Nanoparticles
Description: Researchers are studying ways to couple contrast agents with nanoparticles in order to "see" where they go and validate the targeted delivery of nanomedicines to tumors. Here, therapeutic nanoparticles tagged with a fluorescent molecule have selectively accumulated in a mouse’s tumor (yellow, circled in right panel). Simultaneously, luminescent 18F-fluorodeoxyglucose (FDG) Cerenkov imaging was used to confirm tumor location (circled in middle panel), with multicolors indicating different FDG absorption rates. FDG also accumulated in the mouse’s brain. The tumor location was also confirmed by a PET scan (circled, left panel).

This image is part of the following collections:
Nanotechnology Image Library
NCI Cancer Close Up 2017
Topics/Categories: Science and Technology -- Nanotechnology
Type: Color, Photo
Source: National Cancer Institute \ Washington University in St. Louis
Creator: Kvar Black, Samuel Achilefu
Date Created: June 2016
Date Added: March 20, 2017
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.