Nanoparticles Deliver Theranostic Imaging Agent

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Title: Nanoparticles Deliver Theranostic Imaging Agent
Description: A protein called Prostate Specific Membrane Antigen (PSMA-1) is highly expressed by prostate cancer cells. Here, gold nanoparticles targeted to PSMA-1 selectively deliver an imaging agent and a drug called Pc4 (red, middle panel) to PSMA-expressing cells (blue, middle panel). In mice, the nanoparticles are targeted to the tumor (right panel, nanoparticles in red) but not healthy tissue (left panel). The goal of this nanotechnology is to provide surgical guidance for prostate tumor resection and therapeutic intervention when surgery is insufficient.

This image is part of the following collections:
Nanotechnology Image Library
NCI Cancer Close Up 2017
Topics/Categories: Cancer Types -- Prostate Cancer
Science and Technology -- Nanotechnology
Type: Color, Photo
Source: National Cancer Institute \ Case Western Reserve University
Creator: Joey Mangadlao, Xinning Wang, Christopher McCleese, Clemens Burda, James Basilion
Date Created: November 2016
Date Added: March 20, 2017
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.