Drosophila Wing Cells

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Title: Drosophila Wing Cells
Description: The human CBFA2T3-GLIS2 fusion protein is a key driver of pediatric acute megakaryoblastic leukemia (AMKL), and confers a poor prognosis. Researchers found a way to express CBFA2T3-GLIS2 (red) in larval Drosophila (fruit fly) wing disc cells, confirming a major role for the BMP signaling pathway. This pathway may provide a target for new therapies. Nuclei (green) and actin filaments (purple) are also shown.

This image was originally submitted as part of the 2016 NCI Cancer Close Up project and selected for exhibit.

This image is part of the NCI Cancer Close Up 2016 collection.

See also https://visualsonline.cancer.gov/closeup2016.
Topics/Categories: Cancer Types -- Childhood / Pediatric Cancers
Science and Technology -- Genetics
Type: Color, Photo
Source: National Cancer Institute \ St. Jude Children's Research Hospital
Creator: Suresh Marada
Date Created: October 2011
Date Added: April 11, 2016
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.