HPV-16 E5 Oncoprotein

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Title: HPV-16 E5 Oncoprotein
Description: A koilocyte is a squamous epithelial cell that has undergone structural changes as a result of infection by human papillomavirus (HPV). This image of a koilocyte shows human ectocervical cells (HEC) expressing HPV-16 E5 oncoprotein, and immortalized with HPV-16 E6 and E7 oncoproteins. Formation of koilocytes requires cooperation between HPV E5 and E6 oncoproteins. The cell culture is stained with hematoxylin and eosin (H&E).

This image was originally submitted as part of the 2016 NCI Cancer Close Up project.

This image is part of the NCI Cancer Close Up 2016 collection.

See also https://visualsonline.cancer.gov/closeup2016.
Topics/Categories: Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo
Source: National Cancer Institute \ Georgetown Lombardi Comprehensive Cancer Center
Creator: Ewa Krawczyk
Date Created: 2006
Date Added: April 11, 2016
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.