Lung Cancer Metastasis

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Title: Lung Cancer Metastasis
Description: This image shows how lung cancer cells invade surrounding tissues and start to spread (metastasis). These lung cancer cells have a mutation of a gene called LKB1 (in green) that promotes invasion. Actin, a cytoskeletal protein, is in red, and the cell nucleus is blue. These H157 lung cancer cells are expressing a GFP-tagged piece of LKB1 to disrupt its normal function. Spheroids of these cells were embedded in a 3-D collagen matrix with cells invading for 24 hours.

This image was originally submitted as part of the 2016 NCI Cancer Close Up project.

This image is part of the NCI Cancer Close Up 2016 collection.

See also https://visualsonline.cancer.gov/closeup2016.
Topics/Categories: Cancer Types -- Lung Cancer
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo
Source: National Cancer Institute \ Winship Cancer Institute of Emory University
Creator: Scott Wilkinson, Adam Marcus
Date Created: March 2015
Date Added: April 11, 2016
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.