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As shown here, pancreatic cancer is associated with a vast desmoplastic reaction in which the connective tissue around the tumor thickens and scars. Tests similar to the one depicted here help distinguish between "good" and "bad" stromal reactions. Researchers hope this could allow the design of therapies that will reprogram tumor-stromal interaction. Cancerous cells are in red; nuclei are in blue; stroma/desmoplasia is in cyan; and stroma-specific markers are in yellow and green while marker overlays appear white.
This image was originally submitted as part of the 2016 NCI Cancer Close Up project and selected for exhibit.
This image is part of the NCI Cancer Close Up 2016 collection.
See also https://visualsonline.cancer.gov/closeup2016.
Cancer Types -- Pancreatic Cancer
Cells or Tissue -- Abnormal Cells or Tissue
|Source:||National Cancer Institute \ Fox Chase Cancer Center|
|Creator:||Neelima Shah and Edna Cukierman|
|Date Added:||April 11, 2016|
|Reuse Restrictions:||None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.|