Mimicking Multiple Myeloma

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Title: Mimicking Multiple Myeloma
Description: To understand how multiple myeloma cells grow in their native environment (the bones), researchers have sought ways to mimic those conditions in the laboratory. Tumor cells grow, migrate, and resist therapy very differently in 3D versus 2D culture conditions. This image shows myeloma tumor cells (in green) and bone cells (red) growing on a scaffold made of silk protein (purple), which is designed to resemble bone material. By using a patient's own cells, these models enable efficient screening of patient-specific responses to therapeutics and interactions with bone marrow cells.

This image was originally submitted as part of the 2016 NCI Cancer Close Up project and selected for exhibit.

This image is part of the NCI Cancer Close Up 2016 collection.

See also https://visualsonline.cancer.gov/closeup2016.
Topics/Categories: Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo
Source: National Cancer Institute \ Dana-Farber Harvard Cancer Center
Creator: Michaela Reagan (Maine Medical Center Research Institute)
Date Created: 2015
Date Added: April 11, 2016
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.