Focal Adhesions in Breast Cancer
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|Title:||Focal Adhesions in Breast Cancer|
Some breast cancers overexpress a type of enzyme called Nek3, which plays a role in how a cell organizes itself and moves throughout the body. This image of breast cancer cells overexpressing an inhibitory form of Nek3 (in red) reveals marked enlargement of focal adhesions and its associated proteins such as paxillin (in pink), which help the cell's cytoskeleton (actin, in green) connect to surrounding tissues. Nuclear DNA is pictured in in blue.
This image was originally submitted as part of the 2016 NCI Cancer Close Up project.
Cancer Types -- Breast Cancer
Cells or Tissue -- Abnormal Cells or Tissue
|Type:||Color, Photo (JPEG format)|
|Source:||National Cancer Institute \ Massey Cancer Center at Virginia Commonwealth Univ.|
|Creator:||Katherine Harrington, Charles V. Clevenger|
|Date Created:||December 2015|
|Date Added:||April 11, 2016|
|Reuse Restrictions:||None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.|