Spheroids Cultured Under Normoxia
|Title:||Spheroids Cultured Under Normoxia|
This image shows a cultured tumor spheroid under 21 percent oxygen, in a state of normoxia. Hypoxic areas of the spheroid are marked in green, with nuclear DIPA co-staining (blue). As tumors grow, they outpace the surrounding blood vessels' ability to provide enough oxygen, a state known as hypoxia. Rather than killing the tumor, however, hypoxia somehow triggers changes in cancer cell metabolism that allow for the tumor's continuous growth and spread into nearby tissues.
This image was originally submitted as part of the 2016 NCI Cancer Close Up project.
This image is part of the NCI Cancer Close Up 2016 collection.
See also https://visualsonline.cancer.gov/closeup2016.
|Topics/Categories:||Cells or Tissue -- Normal Cells or Tissue|
|Source:||National Cancer Institute \ Simmons Comprehensive Cancer Center at the Univ. of Texas|
|Date Created:||August 2013|
|Date Added:||April 11, 2016|
|Reuse Restrictions:||None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.|