Normal Mouse Mammary Cells

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Title: Normal Mouse Mammary Cells
Description: Mouse cells that have been taken from the mammary gland are placed into special plates and allowed to grow into 3D sphere formations. These spheres react more like in vivo mammary glands and retain many qualities of the normal gland, compared to growing cells as sheets on a plate. We can use these spheres to look at gene expressions, investigative drug treatments and other manipulations that we might not be able to do directly in the mouse. Sphere shown here was stained with hematoxylin and eosin to distinguish structural features. Hemotoxylin stains blue and binds to negative regions such as the nucleus containing DNA while eosin stains red and binds to positive regions such as proteins in the stroma.

This image was originally submitted as part of the 2016 NCI Cancer Close Up project.
Topics/Categories: Cells or Tissue -- Normal Cells or Tissue
Type: Color, Photo (JPEG format)
Source: National Cancer Institute \ Georgetown Lombardi Comprehensive Cancer Center
Creator: Sahar Alothman, Weisheng Wang, Priscilla A. Furth
Date Created: September 2015
Date Added: April 11, 2016
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.