Lung Cancer Metastasis

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Title: Lung Cancer Metastasis
Description: This image shows how lung cancer cells invade surrounding tissues and start to spread (metastasis). These lung cancer cells have a mutation of a gene called LKB1 (in green) that promotes invasion. Actin, a cytoskeletal protein, is in red, and the cell nucleus is blue. These H157 lung cancer cells are expressing a GFP-tagged piece of LKB1 to disrupt its normal function. Spheroids of these cells were embedded in a 3-D collagen matrix with cells invading for 24 hours.

This image was originally submitted as part of the 2016 NCI Cancer Close Up project.
Topics/Categories: Cancer Types -- Lung Cancer
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo (JPEG format)
Source: National Cancer Institute \ Winship Cancer Institute of Emory University
Creator: Scott Wilkinson, Adam Marcus
Date Created: March 2015
Date Added: April 11, 2016
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.