Molecular Pathways in Human Breast Cancer Cells

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Title: Molecular Pathways in Human Breast Cancer Cells
Description: Human breast cancer cells (nuclei, blue) expressing pMAPKAPK2 (green) and beta-catenin (red). An understanding of how cells, both cancerous and normal, communicate with their environment is important in cancer research. Extracellular signals are transduced through transmembrane receptors and intracellular signaling cascades to alter cell behavior. Molecular signaling by p38/MAPKAPK2 and beta-catenin are involved in the regulation of cell proliferation, gene expression, and cell motility. This image was taken to analyze the activity of these specific molecular pathways.

This image was originally submitted as part of the 2015 NCI Cancer Close Up project.
Topics/Categories: Cancer Types -- Breast Cancer
Cells or Tissue -- Abnormal Cells or Tissue
Type: Color, Photo (JPEG format)
Source: NCI Center for Cancer Research
Creator: Christina Stuelten and Anita Roberts
Date Created: July 2005
Date Added: April 9, 2015
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.