TGF-beta Signaling in Human Breast Cancer Cells
Title: | TGF-beta Signaling in Human Breast Cancer Cells |
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Description: |
Active TGF-beta (green) and latency-associated factor (red) in human breast cancer cells (nuclei, blue). TGF-beta is a pleiotropic signaling molecule found in the extracellular environment of cells that helps suppress tumors and promotes cancer metastasis. TGF-beta is typically found in an inactive form where the active TGF-beta is bound to latency-associated peptide (LAP). Only after dissociation of LAP from TGF-beta can cells sense active TGF-beta. This image measures signaling by TGF-beta in a human breast cancer cell line. This image was originally submitted as part of the 2015 NCI Cancer Close Up project. |
Topics/Categories: |
Cancer Types -- Breast Cancer Cells or Tissue -- Abnormal Cells or Tissue |
Type: | Color, Photo (JPEG format) |
Source: | NCI Center for Cancer Research |
Creator: | Christina Stuelten and Anita Roberts |
Date Created: | June 2005 |
Date Added: | April 9, 2015 |
Reuse Restrictions: | None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above. |