A Tubular DNA Nanodevice as a Sirna/Chemo-Drug Co-Delivery Vehicle for Combined Cancer Therapy

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Title: A Tubular DNA Nanodevice as a Sirna/Chemo-Drug Co-Delivery Vehicle for Combined Cancer Therapy
Description: Atomic force microscopy (AFM) image of DNA nanodevice with glutathione (GSH). The device serves as a vehicle for siRNA-loaded DNA origami co-assembled with multiple functional moieties including tumor-penetrating ligands and stimuli-responsive DNA locks.

Source: Wang Z, Song L, Liu Q, Tian R, Shang Y, Liu F, Liu S, Zhao S, Han Z, Sun J, Jiang Q, Ding B. A Tubular DNA Nanodevice as a siRNA/Chemo-Drug Co-delivery Vehicle for Combined Cancer Therapy. Angew Chem Int Ed Engl. 2021 Feb 1;60(5):2594-2598. doi: 10.1002/anie.202009842. Epub 2020 Dec 1. PMID: 33089613.

See also pubmed.ncbi.nlm.nih.gov/33089613/.
Topics/Categories: Science and Technology -- Nanotechnology
Type: Color, Photo (JPEG format)
Source: National Cancer Institute (NCI)
Date Created: Unknown
Date Added: November 15, 2023
Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and, where possible, the creator listed above.